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Search Results for " bet bromodomain inhibitor 2 "

11

Compounds

Cat No. Product Name Synonyms Targets
T62655 BET bromodomain inhibitor 2
BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).
T6032 Birabresib OTX-015,OTX015 (MK 8628/Birabresib),MK-8628 Epigenetic Reader Domain
Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity.
T19618 (R)-(-)-JQ1 Enantiomer Epigenetic Reader Domain
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
T3504 AZD5153 6-Hydroxy-2-naphthoic acid AZD5153,AZD-5153 HNT salt Epigenetic Reader Domain
AZD5153 6-Hydroxy-2-naphthoic acid (AZD5153) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.
T19935 XD14 Epigenetic Reader Domain
XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
T10773 CF53 Epigenetic Reader Domain , CDK
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT B...
T12558 PROTAC BET-binding moiety 2 Others
PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
T39998 BET bromodomain inhibitor 1
BET bromodomain inhibitor 1 is an orally active, selective inhibitor of bromodomain and extra-terminal (BET) proteins. It specifically inhibits BRD4 with an IC50 of 2.6 nM. Additionally, BET bromodomain inhibitor 1 demon...
T74899 GXH-II-052
GXH-II-052 is a potent bivalent inhibitor targeting the bromodomain and extraterminal domain (BET). It exhibits significant binding affinity to various BET proteins, including BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, and ...
T74898 NC-III-49-1
NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain (BET) inhibitor with significant affinity for several BRD4 and BRDT isoforms, demonstrated by its Kd values of 0.095 nM for BRD4-1, 0.32 nM for BRD4-2...
T36103 TW9 TW9
TW9 is a dual inhibitor of bromodomain 2 (BD2) in bromodomain-containing protein 4 (BRD4) and histone deacetylase 1 (HDAC1; IC50s = 0.074 and 0.29 μM, respectively).1It is selective for BD2 over BD1 in BRD4 (IC50= 0.72 μ...
TargetMol